Eye-lens specific protein, 47 kD, that co-assembles with filensin (3 phakinin molecules per filensin) to form beaded-chain intermediate filaments. Phakinin has very strong sequence homology with cytokeratins but lacks the rod domains that are involved in filament formation. It is effectively a tail-less intermediate filament protein.

Dictionary of molecular biology. 2004.

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  • BFSP2 — Beaded filament structural protein 2, phakinin, also known as BFSP2, is a human gene.cite web | title = Entrez Gene: BFSP2 beaded filament structural protein 2, phakinin| url = Cmd=ShowDetailView… …   Wikipedia

  • BFSP1 — Beaded filament structural protein 1, filensin, also known as BFSP1, is a human gene.cite web | title = Entrez Gene: BFSP1 beaded filament structural protein 1, filensin| url = Cmd=ShowDetailView… …   Wikipedia

  • beaded filaments — (= beaded chain filaments) Intermediate filaments found in the lens fibre cells of the eye: composed of filensin and phakinin …   Dictionary of molecular biology

  • filensin — Protein (100 kD) of the intermediate filament family found in lens fibre cells. Binds to vimentin and co assembles with phakinin to form the lens specific intermediate filament system referred to as beaded chain filaments. Filensin differs from… …   Dictionary of molecular biology

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